Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439308 | 0.86 | MAOB (0.44) | KMT2ASMN1; SMN2MAOBFFAR1ALDH1A1 | |
| SCHEMBL20439307 | 0.86 | MAOB (0.44) | KMT2ASMN1; SMN2MAOBFFAR1ALDH1A1 | |
| SCHEMBL20439319 | 0.85 | SCN4A (0.48) | KMT2ASMN1; SMN2MAOBLMNAMAPT | |
| SCHEMBL5355437 | 0.85 | SCN4A (0.48) | KMT2ASMN1; SMN2MAOBLMNAMAPT | |
| SCHEMBL20439314 | 0.83 | SCN4A (0.43) | KMT2ASMN1; SMN2MAOBLMNAMAPT | |
| SCHEMBL20425127 | 0.81 | ERN1 (0.41) | SMN1; SMN2PARP15MAOBFFAR1PPARD | |
| SCHEMBL31725937 | 0.78 | MAOB (0.58) | SMN1; SMN2PARP15MAOBLMNAALDH1A1 | |
| SCHEMBL6119729 | 0.78 | MAOB (0.58) | SMN1; SMN2PARP15MAOBLMNAALDH1A1 | |
| SCHEMBL18044481 | 0.78 | MAOB (0.58) | SMN1; SMN2MAOBFFAR1PPARDLMNA | |
| SCHEMBL20439449 | 0.76 | NPC1 (0.49) | SMN1; SMN2FFAR1PPARDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |