Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.48 |
| ▸ | PPARD | Q03181 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439321 | 0.85 | LMNA (0.57) | NPC1RAB9ASMN1; SMN2FFAR1L3MBTL1 | |
| SCHEMBL18044481 | 0.77 | MAOB (0.58) | HPGDSMN1; SMN2FFAR1PPARDL3MBTL1 | |
| SCHEMBL31725937 | 0.77 | MAOB (0.58) | SMN1; SMN2L3MBTL1PTPN1 | |
| SCHEMBL6119729 | 0.77 | MAOB (0.58) | SMN1; SMN2L3MBTL1PTPN1 | |
| SCHEMBL20439378 | 0.76 | KMT2A (0.40) | SMN1; SMN2FFAR1PPARDL3MBTL1 | |
| SCHEMBL20439423 | 0.75 | LMNA (0.56) | NPC1RAB9ASMN1; SMN2FFAR1PPARD | |
| SCHEMBL20425127 | 0.74 | ERN1 (0.41) | HPGDSMN1; SMN2FFAR1PPARDPTPN1 | |
| SCHEMBL4364373 | 0.74 | NR4A2 (0.55) | NPC1HPGDRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9811686 | 0.74 | SMN1; SMN2 (0.60) | NPC1HPGDRAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL1515704 | 0.73 | HTT (0.62) | NPC1HPGDRAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |