Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.54 |
| ▸ | PPARD | Q03181 | 5/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27882779 | 0.87 | MAOB (0.58) | MAOBFFAR1PPARD | |
| SCHEMBL15365 | 0.87 | MAOB (0.58) | MAOBFFAR1ALOX5LMNAALDH1A1 | |
| SCHEMBL18623122 | 0.83 | MAOB (0.62) | MAOBALOX5LMNAALDH1A1MAPT | |
| SCHEMBL2090976 | 0.83 | MAOB (0.62) | MAOBALOX5LMNAALDH1A1MAPT | |
| SCHEMBL20252664 | 0.83 | MAOB (0.57) | MAOBFFAR1PPARDALOX5ALDH1A1 | |
| SCHEMBL1128493 | 0.83 | FFAR1 (0.59) | FFAR1PPARDALOX5 | |
| SCHEMBL8184228 | 0.82 | MAOB (0.60) | MAOBALOX5LMNAALDH1A1MAPT | |
| SCHEMBL30148511 | 0.82 | MAOB (0.60) | MAOBALOX5LMNAALDH1A1MAPT | |
| SCHEMBL13802180 | 0.82 | MAOB (0.60) | MAOBFFAR1PPARDALOX5LMNA | |
| SCHEMBL15817 | 0.81 | ALOX5 (0.61) | MAOBALOX5LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067351-B1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | JENKEM TECH CO LTD TIANJIN (CN) | 2019-02-06 | — | — | EP | disclosed |
| US-9925171-B2 | Compound having higher inhibitory activity on protein kinase G and preparation method thereof | Jenkem Technology Co., Ltd., (Tianjin) (CN) | 2018-03-27 | — | — | US | disclosed |
| US-20170119736-A1 | COMPOUND HAVING HIGHER INHIBITORY ACTIVITY ON PROTEIN KINASE G AND PREPARATION METHOD THEREOF | Jenkem Technology Co., Ltd., (Tianjin) (CN) | 2017-05-04 | — | — | US | disclosed |
| US-9567319-B2 | Compound having higher inhibitory activity on protein kinase G and preparation method thereof | JENKEM TECHNOLOGY CO. LTD., (TIANJIN) (CN) | 2017-02-14 | — | — | US | disclosed |
| US-20160304501-A1 | COMPOUND HAVING HIGHER INHIBITORY ACTIVITY ON PROTEIN KINASE G AND PREPARATION METHOD THEREOF | Jenkem Technology Co., Ltd., (Tianjin) (CN) | 2016-10-20 | — | — | US | disclosed |
| EP-3067351-A1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2016-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304501-A1 | COMPOUND HAVING HIGHER INHIBITORY ACTIVITY ON PROTEIN KINASE G AND PREPARATION METHOD THEREOF | PRKCG, PRKG2, PKN3 | MAOB 1897/4885FFAR1 1354/4885PPARD 3438/4885 |
| US-20170119736-A1 | COMPOUND HAVING HIGHER INHIBITORY ACTIVITY ON PROTEIN KINASE G AND PREPARATION METHOD THEREOF | PRKCG, PRKG2, PKN3 | MAOB 1897/4885FFAR1 1354/4885PPARD 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.