Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439399 | 1.00 | BCL2 (0.43) | BCL2ACACBPTPN1HDAC8LTA4H | |
| SCHEMBL5354486 | 0.83 | BCL2 (0.44) | BCL2ACACBPTPN1HDAC8LTA4H | |
| SCHEMBL20439435 | 0.83 | BCL2 (0.44) | BCL2ACACBPTPN1HDAC8LTA4H | |
| SCHEMBL20425274 | 0.81 | BCL2 (0.50) | BCL2ACACBPTPN1LTA4HALOX5 | |
| SCHEMBL20439387 | 0.81 | BCL2 (0.50) | BCL2ACACBPTPN1LTA4HALOX5 | |
| SCHEMBL20439315 | 0.79 | PTPN1 (0.41) | BCL2ACACBPTPN1HDAC8LTA4H | |
| SCHEMBL20439384 | 0.78 | PTPN1 (0.43) | BCL2PTPN1MEN1KMT2APRKCA | |
| SCHEMBL30703570 | 0.76 | BCL2 (0.51) | BCL2ACACBPTPN1LTA4HALOX5 | |
| SCHEMBL191550 | 0.74 | ATM (0.55) | BCL2ACACBPTPN1LTA4HPRKCA | |
| SCHEMBL191549 | 0.74 | ATM (0.55) | BCL2ACACBPTPN1LTA4HPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |