Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425274 | 1.00 | BCL2 (0.50) | BCL2ACACBPTPN1GPR88ALOX5 | |
| SCHEMBL20425136 | 0.85 | LMNA (0.56) | ACACBGPR88ALOX5LTA4HLMNA | |
| SCHEMBL3350991 | 0.85 | PTPN1 (0.50) | BCL2ACACBPTPN1ALOX5LTA4H | |
| SCHEMBL30703570 | 0.85 | BCL2 (0.51) | BCL2ACACBPTPN1GPR88ALOX5 | |
| SCHEMBL13211538 | 0.84 | CTSK (0.52) | GPR88PPARA | |
| SCHEMBL16622532 | 0.84 | CTSK (0.52) | GPR88PPARA | |
| SCHEMBL1908632 | 0.84 | CTSK (0.52) | GPR88PPARA | |
| SCHEMBL4731613 | 0.84 | CTSK (0.52) | GPR88PPARA | |
| SCHEMBL191549 | 0.83 | ATM (0.55) | BCL2ACACBPTPN1LTA4HPRKCA | |
| SCHEMBL191550 | 0.83 | ATM (0.55) | BCL2ACACBPTPN1LTA4HPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |