Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354486 | 0.94 | BCL2 (0.44) | PTPN1PPARABCL2CTSSPRKCA | |
| SCHEMBL20439435 | 0.94 | BCL2 (0.44) | PTPN1PPARABCL2CTSSPRKCA | |
| SCHEMBL20439315 | 0.92 | PTPN1 (0.41) | PTPN1PPARABCL2AAK1CTSS | |
| SCHEMBL20439373 | 0.83 | AAK1 (0.43) | PPARAAAK1ALDH1A1HTTNPSR1 | |
| SCHEMBL20439398 | 0.83 | AAK1 (0.43) | PPARAAAK1ALDH1A1HTTNPSR1 | |
| SCHEMBL20439386 | 0.83 | MAOB (0.41) | PTPN1GPR34FFAR1FFAR4MEN1 | |
| SCHEMBL20439399 | 0.78 | BCL2 (0.43) | PTPN1PPARABCL2PRKCAPRKCD | |
| SCHEMBL20439397 | 0.78 | BCL2 (0.43) | PTPN1PPARABCL2PRKCAPRKCD | |
| SCHEMBL5350616 | 0.76 | PRKCA (0.54) | PTPN1PPARABCL2PRKCAPRKCD | |
| SCHEMBL1553475 | 0.76 | PRKCA (0.54) | PTPN1PPARABCL2PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |