Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425665 | 0.92 | HDAC6 (0.58) | HPGDSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL16523571 | 0.84 | CA1 (0.61) | HPGDSMN1; SMN2ALDH1A1LMNAHDAC6 | |
| SCHEMBL3808915 | 0.83 | ABHD6 (0.59) | HPGDSMN1; SMN2HTTABHD6MEN1 | |
| SCHEMBL31598007 | 0.83 | ABHD6 (0.59) | HPGDSMN1; SMN2HTTABHD6MEN1 | |
| SCHEMBL4279383 | 0.83 | HPGD (0.73) | HPGDSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL30277860 | 0.83 | HPGD (0.73) | HPGDSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL20425631 | 0.82 | MAPK1 (0.51) | HPGDSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL24503025 | 0.81 | ABHD6 (0.54) | HPGDSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL20046984 | 0.80 | PDE4B (0.54) | HPGDSMN1; SMN2HTTALDH1A1ABHD6 | |
| SCHEMBL13717628 | 0.80 | GAA (0.55) | HPGDSMN1; SMN2HTTALDH1A1ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140876-A1 | NRF2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |