Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | NAMPT | P43490 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30277860 | 1.00 | HPGD (0.73) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL10414745 | 0.88 | HPGD (0.74) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL14818002 | 0.87 | HPGD (0.66) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL10414730 | 0.87 | HPGD (0.72) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL13211911 | 0.87 | HTT (0.71) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL31396748 | 0.87 | HPGD (0.66) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL12459664 | 0.87 | CA1 (0.70) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL94624 | 0.87 | HPGD (0.66) | HPGDLMNAALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL4167985 | 0.87 | NAMPT (0.64) | HPGDLMNAALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL16523571 | 0.84 | CA1 (0.61) | HPGDLMNAALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534793-B2 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM P.L.C. (GB) | 2009-05-19 | — | — | US | claimed |
| US-20230145822-A1 | SMALL MOLECULES INDUCING THE DEGRADATION OF THE CELLULAR PRION PROTEIN | FONDAZIONE TELETHON (IT) | 2023-05-11 | — | — | US | disclosed |
| US-20230145822-A1 | SMALL MOLECULES INDUCING THE DEGRADATION OF THE CELLULAR PRION PROTEIN | FONDAZIONE TELETHON (IT) | 2023-05-11 | — | — | US | disclosed |
| WO-2022258986-A1 | COMPOUNDS USEFUL IN THE TREATMENT OR PREVENTION OF A PRMT5-MEDIATED DISORDER | Argonaut Therapeutics Limited (GB) | 2022-12-15 | — | — | WO | disclosed |
| EP-1773786-B1 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-26 | — | — | EP | disclosed |
| US-9278905-B2 | Production method for compound comprising amino group and/or hydroxyl group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-03-08 | — | — | US | disclosed |
| US-9278905-B2 | Production method for compound comprising amino group and/or hydroxyl group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-03-08 | — | — | US | disclosed |
| EP-2867210-A1 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN OR A SALT THEREOF | Pharmathen S.A. (GR) | 2015-05-06 | — | — | EP | disclosed |
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| EP-2821389-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | Kyushu University, National University Corporation (JP) | 2015-01-07 | — | — | EP | disclosed |
| WO-2014005601-A1 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN OR A SALT THEREOF | PHARMATHEN S.A. (GR) | 2014-01-09 | — | — | WO | disclosed |
| US-20090075978-A1 | SUBSTITUTED PROPIOLIC ACID AMIDES AND THEIR USE FOR PRODUCING DRUGS | GRUNENTHAL GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| WO-2007079957-A1 | SUBSTITUTED PROPIOLIC ACID AMIDES AND THEIR USE FOR PRODUCING DRUGS | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | CA7, DAO, CA4 | HPGD 264/4885LMNA 2891/4885ALDH1A1 732/4885 |
| US-20090075978-A1 | SUBSTITUTED PROPIOLIC ACID AMIDES AND THEIR USE FOR PRODUCING DRUGS | PCCA, PPARA, PTGES | HPGD 64/4885LMNA 2581/4885ALDH1A1 360/4885 |
| US-20230145822-A1 | SMALL MOLECULES INDUCING THE DEGRADATION OF THE CELLULAR PRION PROTEIN | PRNP, PPIE, PPIC | HPGD 1484/4885LMNA 1493/4885ALDH1A1 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.