SCHEMBL204405

SCHEMBL204405

C=C[Si](C)(N(CC)C(C)=O)N(CC)C(C)=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11765231 0.83 CA12 (0.30)
SCHEMBL3804089 0.81 ALDH1A1 (0.33) ALDH1A1
SCHEMBL508319 0.80 CA12 (0.34) TSHR
SCHEMBL11124760 0.76
SCHEMBL11404805 0.76 ALDH1A1 (0.37) ALDH1A1
SCHEMBL11678374 0.74 CHRM1 (0.38) ALDH1A1
SCHEMBL9422287 0.74 CHRM1 (0.33) ALDH1A1
SCHEMBL203529 0.74 CHRM1 (0.33) ALDH1A1
SCHEMBL28790102 0.72 CHRM1 (0.32) ALDH1A1
SCHEMBL202575 0.70 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363487-B1 SILICONE COMPOSITIONS AND THEIR PREPARATION DOW SILICONES CORP (US) 2025-03-19 EP claimed
US-20240294711-A1 SILICONE COMPOSITIONS AND THEIR PREPARATION DOW SILICONES CORP (US) 2024-09-05 US claimed
CN-117377715-A Silicone composition and preparation thereof 美国陶氏有机硅公司 2024-01-09 CN claimed
CN-110964050-B Preparation method of methylvinyldi (N-ethylacetamido) silane 仙桃市蓝化有机硅有限公司 2022-04-29 CN claimed
US-20140087082-A1 Room Temperature Vulcanisable Silicone Compositions DOW CORNING CORPORATION (US) 2014-03-27 US claimed
WO-2012166692-A1 ROOM TEMPERATURE VULCANISABLE SILICONE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-12-06 WO claimed
US-4683251-A Room temperature-curable organopolysiloxane composition containing a photosensitizer TORAY SILICONE CO., LTD. (JP) 1987-07-28 US claimed
EP-0215215-A2 Room temperature-curable organopolysiloxane composition containing a photosensitizer Toray Silicone Company, Ltd. (JP) 1987-03-25 EP claimed
EP-0210442-A2 Room temperature-curable organopolysiloxane composition Toray Silicone Company, Ltd. (JP) 1987-02-04 EP claimed
EP-4363487-B1 SILICONE COMPOSITIONS AND THEIR PREPARATION DOW SILICONES CORP (US) 2025-03-19 EP disclosed
US-20240294711-A1 SILICONE COMPOSITIONS AND THEIR PREPARATION DOW SILICONES CORP (US) 2024-09-05 US disclosed
CN-117377715-A Silicone composition and preparation thereof 美国陶氏有机硅公司 2024-01-09 CN disclosed
US-11814553-B2 Adhesive DOW SILICONES CORPORATION (US) 2023-11-14 US disclosed
CN-112823193-B Adhesive agent 美国陶氏有机硅公司 2023-09-15 CN disclosed
US-4614760-A POLYSILOXANES DOW CORNING CORPORATION (US) 1986-09-30 US disclosed
US-4555420-A DIFUNCTIONAL NITROGEN-CONTAINING SILANE CURING AGENTS; LOW MODULUS ENCAPPED POLYSILOXANES GENERAL ELECTRIC COMPANY (US) 1985-11-26 US disclosed
US-4552919-A Room temperature-curable polyorganosiloxane composition whose cured products resist soiling TORAY SILICONE COMPANY, LTD. (JP) 1985-11-12 US disclosed
EP-0131446-A2 Room temperature-curable polyorganosiloxane composition whose cured products resist soiling Toray Silicone Co., Ltd. (JP) 1985-01-16 EP disclosed
US-4477606-A Water resistant room temperature vulcanizable polyorganosiloxane compositions and method for preparing same TORAY SILICONE CO., LTD. (JP) 1984-10-16 US disclosed
EP-0106363-A2 Water resistant room temperature vulcanizable polyorganosiloxane compositions and method for preparing same Toray Silicone Co., Ltd. (JP) 1984-04-25 EP disclosed