Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18532085 | 0.85 | MAPK8 (0.35) | SLC6A4CACNA1HCYP11B2CASP3SCARB1 | |
| SCHEMBL15687222 | 0.76 | PTGDR2 (0.35) | ALOX5APSLC6A4CACNA1HCASP3MEN1 | |
| SCHEMBL29889423 | 0.74 | ADORA2A (0.53) | SLC6A4CACNA1HDRD2DRD3CYP11B2 | |
| SCHEMBL13106345 | 0.74 | ADORA2A (0.53) | SLC6A4CACNA1HDRD2DRD3CYP11B2 | |
| SCHEMBL20458071 | 0.74 | KDM4E (0.44) | KMT2A | |
| SCHEMBL13106485 | 0.73 | AURKA (0.37) | SLC6A4CACNA1HCYP11B2CASP3SCARB1 | |
| SCHEMBL4080159 | 0.73 | AURKA (0.39) | SLC6A4CACNA1HCYP11B2CASP3SCARB1 | |
| SCHEMBL31586549 | 0.73 | CASP3 (0.39) | SLC6A4CACNA1HCYP11B2CASP3GSK3B | |
| SCHEMBL29584180 | 0.73 | AURKA (0.37) | SLC6A4CACNA1HCYP11B2CASP3SCARB1 | |
| SCHEMBL30200588 | 0.73 | CACNA1H (0.37) | SLC6A4CACNA1HCYP11B2CASP3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215757-A1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | CORNELL UNIVERSITY | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215757-A1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | FSCN1, MTPN, MYOF | ALOX5AP 937/4885SLC6A4 1918/4885S1PR1 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.