SCHEMBL2044265

SCHEMBL2044265

CC(=O)O/N=C(\CCC/C(=N\OC(C)=O)c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 12/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.48
PPARG P37231 11/20 0.46
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044266 1.00 PPARA (0.51) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL9897959 0.94 L3MBTL1 (0.51) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL9897957 0.94 L3MBTL1 (0.51) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL2048158 0.93 PPARA (0.54) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL2048160 0.93 PPARA (0.54) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL24740675 0.92 CES2 (0.50) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL29227740 0.88 KDM4E (0.49) PPARAL3MBTL1MAPTPKMPPARG
SCHEMBL2051838 0.87 PPARA (0.49) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL2051837 0.87 PPARA (0.49) PPARAL3MBTL1GAAMAPTPKM
SCHEMBL9897583 0.87 NR4A2 (0.50) PPARAL3MBTL1GAAMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed