SCHEMBL2044281

SCHEMBL2044281

O=C(Cl)c1c2ccccc2cc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
KDM4E B2RXH2 3/20 0.65
HPGD P15428 3/20 0.65
HSD17B10 Q99714 2/20 0.65
CYP1A2 P05177 1/20 0.65
GLA P06280 1/20 0.65
CYP2C19 P33261 1/20 0.65
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 1/20 0.42
CYP3A4 P08684 1/20 0.42
TRPM4 Q8TD43 1/20 0.41
MAPT P10636 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41
HTR2A P28223 1/20 0.40
NQO2 P16083 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617716 1.00 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL31424059 0.84 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL30368759 0.83 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL11674250 0.83 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL8854740 0.82 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL11559708 0.81 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL8549079 0.80 ALDH1A1 (0.69) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL4899613 0.79 ALDH1A1 (0.68) ALDH1A1MEN1KMT2AKDM4EHPGD
Anthracene-9-Carboxylic Acid SCHEMBL29352186 0.79 MEN1 (1.00) ALDH1A1MEN1KMT2AKDM4EHPGD
Anthracene-9-Carboxylic Acid SCHEMBL122832 0.79 MEN1 (1.00) ALDH1A1MEN1KMT2AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117659254-A Method for producing cyclic polyelectrolyte and cyclic polyelectrolyte 中国科学技术大学 2024-03-08 CN claimed
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN claimed
US-20100171923-A1 LACTAM POLYMER DERIVATIVES JOHSNON & JOHNSON VISION CARE, INC. 2010-07-08 US claimed
US-20070290174-A1 LACTAM POLYMER DERIVATIVES JOHNSON & JOHNSON VISION CARE, INC. 2007-12-20 US claimed
CN-101065407-A Lactam polymer derivatives JOHNSON & JOHNSON VISION CARE (US) 2007-10-31 CN claimed
EP-1799724-A2 LACTAM POLYMER DERIVATIVES Johnson and Johnson Vision Care, Inc. (US) 2007-06-27 EP claimed
WO-2006039276-A2 LACTAM POLYMER DERIVATIVES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO claimed
US-20060069235-A1 Lactam polymer derivatives JOHNSON & JOHNSON VISION CARE, INC. 2006-03-30 US claimed
US-20250116922-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING RESIST PATTERN JSR CORPORATION (JP) 2025-04-10 US disclosed
CN-118807006-A Preparation method of heparin anticoagulation coating, anticoagulation material and application 复旦大学 2024-10-22 CN disclosed
CN-117659254-A Method for producing cyclic polyelectrolyte and cyclic polyelectrolyte 中国科学技术大学 2024-03-08 CN disclosed
WO-2023248569-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN FORMATION METHOD JSR株式会社 2023-12-28 WO disclosed
CN-111315829-B Small molecule organic dye 巴塞尔大学 2022-11-04 CN disclosed
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN disclosed
US-4413052-A Photopolymerization process employing compounds containing acryloyl group and anthryl group CIBA-GEIGY CORPORATION (US) 1983-11-01 US disclosed
US-4192677-A ELECTROGRAPHIC CHARGE TRANSFER COMPOUNDS RICOH CO., LTD. (JP) 1980-03-11 US disclosed
US-4141729-A 1,3,4-Oxadiazole derivatives and electrophotographic plates containing same RICOH COMPANY, LTD. (JP) 1979-02-27 US disclosed
US-4088772-A TRANQUILIZERS, ANALGESICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-05-09 US disclosed
US-4077977-A Ethenoanthracenes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-03-07 US disclosed
US-4076830-A TRANQUILIZERS, ANALGESICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-02-28 US disclosed