Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene-9-Carboxylic Acid SCHEMBL122832 | 0.82 | MEN1 (1.00) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL29352186 | 0.82 | MEN1 (1.00) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11582793 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL28121546 | 0.80 | MEN1 (0.95) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2044281 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL27733356 | 0.80 | MEN1 (0.95) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL30617716 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL7054301 | 0.80 | MEN1 (0.95) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL28099540 | 0.80 | MEN1 (0.95) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Anthracene-9-Carboxylic Acid SCHEMBL11788252 | 0.80 | MEN1 (0.95) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536208-B1 | 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS | RES CORP TECHNOLOGIES INC (US) | 1998-01-21 | — | — | EP | disclosed |
| EP-0660824-A1 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006771-A9 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | — | 1994-06-09 | — | — | WO | disclosed |
| EP-0536208-A4 | 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0536208-A1 | 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-04-14 | — | — | EP | disclosed |