Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136376 | 1.00 | DRD2 (0.48) | DRD2DRD3GBA1MAPTACHE | |
| SCHEMBL21193607 | 1.00 | DRD2 (0.48) | DRD2DRD3GBA1MAPTACHE | |
| SCHEMBL26128448 | 1.00 | DRD2 (0.48) | DRD2DRD3GBA1MAPTACHE | |
| SCHEMBL26126731 | 1.00 | DRD2 (0.48) | DRD2DRD3GBA1MAPTACHE | |
| SCHEMBL8573261 | 0.87 | ACHE (0.41) | DRD2DRD3MAPTACHEDRD4 | |
| SCHEMBL15921453 | 0.83 | ACHE (0.45) | DRD2DRD3MAPTACHEDRD4 | |
| SCHEMBL15921452 | 0.83 | ACHE (0.45) | DRD2DRD3MAPTACHEDRD4 | |
| SCHEMBL17314313 | 0.83 | ACHE (0.45) | DRD2DRD3MAPTACHEDRD4 | |
| SCHEMBL17314312 | 0.83 | ACHE (0.45) | DRD2DRD3MAPTACHEDRD4 | |
| SCHEMBL17314984 | 0.83 | ACHE (0.45) | DRD2DRD3MAPTACHEDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018137619-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-02 | — | — | WO | disclosed |