Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12025014 | 0.90 | ACHE (0.38) | HRH3KDM4EACHECARM1PRMT6 | |
| SCHEMBL15096958 | 0.90 | ACHE (0.38) | HRH3KDM4EACHECARM1PRMT6 | |
| SCHEMBL12665785 | 0.85 | KDM4E (0.42) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL13656265 | 0.85 | KDM4E (0.42) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL9278459 | 0.81 | ACHE (0.45) | HRH3ACHECARM1PRMT6PRMT1 | |
| SCHEMBL15164245 | 0.78 | KDM4E (0.47) | HRH3KDM4ELMNAMAOB | |
| SCHEMBL10159852 | 0.75 | KDM4E (0.34) | HRH3HRH4KDM4EALPG | |
| SCHEMBL12385800 | 0.73 | KDM4E (0.36) | HRH3KDM4EACHECARM1PRMT6 | |
| SCHEMBL22544216 | 0.73 | KDM4E (0.36) | HRH3KDM4EACHECARM1PRMT6 | |
| SCHEMBL26817743 | 0.73 | ACHE (0.35) | HRH3KDM4EACHECARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215743-A1 | 1,3,4-OXADIAZOLE AMIDE DERIVATIVE COMPOUND AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215743-A1 | 1,3,4-OXADIAZOLE AMIDE DERIVATIVE COMPOUND AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | HDAC1, HDAC6, HDAC2 | HRH3 651/4885HRH4 746/4885KDM4E 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.