Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549159 | 0.81 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2ALDH1A1ALOX15POLB | |
| SCHEMBL20445294 | 0.81 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2ALDH1A1ALOX15MAPT | |
| SCHEMBL20445327 | 0.78 | F2R (0.44) | KMT2ASMN1; SMN2ALDH1A1F2RGAA | |
| SCHEMBL20445364 | 0.78 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2HTTALDH1A1POLB | |
| SCHEMBL28552975 | 0.73 | KDM4E (0.54) | KMT2ACYP2C9HTTALDH1A1ALOX15 | |
| SCHEMBL21794478 | 0.73 | ESR2 (0.45) | KMT2ASMN1; SMN2CYP3A4ALDH1A1ALOX15 | |
| Toluic Acid SCHEMBL28104690 | 0.73 | KMT2A (0.53) | KMT2ASMN1; SMN2CYP3A4CYP2C9HTT | |
| SCHEMBL28557543 | 0.72 | KDM4E (0.49) | KMT2ACYP3A4ALDH1A1ALOX15KDM4E | |
| Phthalic Acid SCHEMBL30717997 | 0.71 | ALDH1A1 (0.61) | KMT2ASMN1; SMN2ALDH1A1ALOX15MYC | |
| Phthalic Acid SCHEMBL8155 | 0.71 | ALDH1A1 (0.61) | KMT2ASMN1; SMN2ALDH1A1ALOX15MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140504-A1 | COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS | PATEL MANOJ K (US) | 2018-08-02 | — | — | WO | disclosed |