Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 15/20 | 0.35 |
| ▸ | NPY1R | P25929 | 9/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.35 |
| ▸ | NPY2R | P49146 | 5/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16260144 | 0.83 | SIRT6 (0.43) | CPB2NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16260140 | 0.83 | SIRT6 (0.40) | CPB2NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16260290 | 0.83 | SIRT6 (0.43) | NPY4RNPY1RNPY5RNPY2RSIRT6 | |
| SCHEMBL16260299 | 0.83 | SIRT6 (0.40) | NPY4RNPY1RNPY5RNPY2RSIRT6 | |
| SCHEMBL27113032 | 0.82 | SIRT6 (0.48) | SIRT6SIRT1 | |
| SCHEMBL27114204 | 0.81 | SIRT6 (0.50) | SIRT6SIRT1 | |
| SCHEMBL13402566 | 0.81 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL16260143 | 0.80 | HPGD (0.36) | NPY4RNPY1RNPY5RNPY2RSIRT6 | |
| SCHEMBL16263607 | 0.80 | SIRT6 (0.38) | CPB2NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL14199839 | 0.80 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180216111-A1 | ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE | SAREPTA THERAPEUTICS, INC. | 2018-08-02 | — | — | US | disclosed |