Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 8/20 | 0.36 |
| ▸ | NPY1R | P25929 | 6/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16260140 | 0.94 | SIRT6 (0.40) | SIRT6SIRT1NMT2NMT1GNAI3 | |
| SCHEMBL16263607 | 0.91 | SIRT6 (0.38) | SIRT6SIRT1NMT2NMT1DPP7 | |
| SCHEMBL16260290 | 0.89 | SIRT6 (0.43) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL16260299 | 0.89 | SIRT6 (0.40) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL27113032 | 0.87 | SIRT6 (0.48) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL27114204 | 0.86 | SIRT6 (0.50) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL16263589 | 0.85 | SIRT6 (0.45) | SIRT6SIRT1NMT2NMT1GNAI3 | |
| SCHEMBL16260143 | 0.85 | HPGD (0.36) | SIRT6SIRT1NPY4RNPY1RNPY2R | |
| SCHEMBL16263611 | 0.84 | NPY4R (0.34) | SIRT6SIRT1DPP7TLR2NPY4R | |
| SCHEMBL20445457 | 0.83 | CPB2 (0.38) | SIRT6SIRT1CPB2NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190002429-A1 | Derivatives of Xanthone Compounds | SINGAPORE HEALTH SERVICES PTE LTD (SG) | 2019-01-03 | — | — | US | disclosed |
| US-20140349918-A1 | DERIVATIVES OF XANTHONE COMPOUNDS | SINGAPORE HEALTH SERVICES PTE LTD. (SG) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002429-A1 | Derivatives of Xanthone Compounds | XDH, XPA, SQLE | SIRT6 1326/4885SIRT1 932/4885NMT2 352/4885 |
| US-20140349918-A1 | DERIVATIVES OF XANTHONE COMPOUNDS | XDH, XPA, SQLE | SIRT6 1326/4885SIRT1 932/4885NMT2 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.