Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20429044 | 0.96 | GAA (0.37) | GAA | |
| SCHEMBL20429045 | 0.95 | GAA (0.36) | GAA | |
| SCHEMBL11500771 | 0.92 | GAA (0.41) | GAAATML3MBTL1MEN1KMT2A | |
| SCHEMBL11170098 | 0.91 | GAA (0.42) | GAAMEN1KMT2A | |
| SCHEMBL20438824 | 0.89 | GAA (0.33) | GAA | |
| SCHEMBL21581490 | 0.84 | GAA (0.36) | GAA | |
| SCHEMBL20428971 | 0.83 | EPHX2 (0.36) | GAAMEN1KMT2A | |
| SCHEMBL26482189 | 0.83 | NAAA (0.40) | GAA | |
| SCHEMBL20438833 | 0.82 | ESR1 (0.44) | GAAALDH1A1 | |
| SCHEMBL20428969 | 0.82 | EPHX2 (0.36) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913897-B2 | Compounds and liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2021-02-09 | — | — | US | disclosed |
| US-20180216005-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913897-B2 | Compounds and liquid-crystalline medium | VIM, NEFM, AQP1 | GAA 4024/4885ATM 1307/4885L3MBTL1 2508/4885 |
| US-20180216005-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | VIM, NEFM, AQP1 | GAA 4024/4885ATM 1307/4885L3MBTL1 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.