Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446020 | 1.00 | ALOX15 (0.32) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL20446021 | 1.00 | ALOX15 (0.32) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL20446053 | 0.80 | CYP2D6 (0.44) | ALOX15THRBBLMCYP1A2CYP2D6 | |
| SCHEMBL16397892 | 0.80 | CYP2D6 (0.44) | ALOX15THRBBLMCYP1A2CYP2D6 | |
| SCHEMBL16397543 | 0.80 | CYP2D6 (0.44) | ALOX15THRBBLMCYP1A2CYP2D6 | |
| SCHEMBL16397787 | 0.80 | CYP2D6 (0.44) | ALOX15THRBBLMCYP1A2CYP2D6 | |
| SCHEMBL1260591 | 0.80 | CYP2D6 (0.44) | ALOX15THRBBLMCYP1A2CYP2D6 | |
| SCHEMBL19002903 | 0.80 | CYP2D6 (0.44) | ALOX15THRBBLMCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1260628 | 0.79 | CYP2D6 (0.43) | ALOX15THRBBLMCYP1A2CYP2D6 | |
| SCHEMBL4305909 | 0.73 | KDM4E (0.55) | ALOX15KDM4EMAPTTHRBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356433-A1 | NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS | CIS Pharma AG (CH) | 2018-08-08 | — | — | EP | disclosed |