SCHEMBL20446053

SCHEMBL20446053

C=CC(=O)OC1CN[C@H](C(=O)O)C1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.44
▸ CYP1A2 P05177 2/20 0.44
▸ ALOX15 P16050 2/20 0.44
▸ CYP2C19 P33261 2/20 0.44
▸ SLC1A3 P43003 1/20 0.44
▸ SLC1A2 P43004 1/20 0.44
▸ SLC1A1 P43005 1/20 0.44
▸ ARG1 P05089 1/20 0.36
▸ LMNA P02545 2/20 0.34
▸ BLM P54132 2/20 0.34
▸ TSHR P16473 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ PMP22 Q01453 1/20 0.34
▸ KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16397543 1.00 CYP2D6 (0.44) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL19002903 1.00 CYP2D6 (0.44) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL1260591 1.00 CYP2D6 (0.44) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL16397892 1.00 CYP2D6 (0.44) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL16397787 1.00 CYP2D6 (0.44) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
Hydrochloric Acid SCHEMBL1260628 0.98 CYP2D6 (0.43) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL27363554 0.82 CHRNB2 (0.34) CYP2D6CYP1A2ALOX15CYP2C19
SCHEMBL20446020 0.80 ALOX15 (0.32) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL20446021 0.80 ALOX15 (0.32) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3
SCHEMBL20446019 0.80 ALOX15 (0.32) CYP2D6CYP1A2ALOX15CYP2C19SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 — — US disclosed
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS BIOPHARMA AG (CH) 2022-12-29 — — US disclosed
EP-4051320-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS Pharma AG (CH) 2022-09-07 — — EP disclosed
CN-114641316-A Biocompatible polymeric drug carriers for delivery of active agents CIS制药股份公司 2022-06-17 — — CN disclosed
US-11008414-B2 Polymer materials for contact lens applications CIS PHARMA AG (CH) 2021-05-18 — — US disclosed
US-20210128735-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS BIOPHARMA AG (CH) 2021-05-06 — — US disclosed
WO-2021084087-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS PHARMA AG (CH) 2021-05-06 — — WO disclosed
EP-3790590-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS Pharma AG (CH) 2021-03-17 — — EP disclosed
CN-112088016-A Biocompatible copolymers containing multiple active agent molecules 化工研究所有限公司 2020-12-15 — — CN disclosed
US-20200283560-A1 New polymer materials for contact lens applications CIS PHARMA AG (CH) 2020-09-10 — — US disclosed
WO-2019215207-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS PHARMA AG (CH) 2019-11-14 — — WO disclosed
EP-3356433-B1 NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS CIS PHARMA AG (CH) 2019-09-18 — — EP disclosed
EP-3356433-A1 NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS CIS Pharma AG (CH) 2018-08-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents MSR1, CD47, SLC43A1 CYP2D6 1675/4885CYP1A2 3829/4885ALOX15 2533/4885
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CD47, DNPEP, MSR1 CYP2D6 2911/4885CYP1A2 3900/4885ALOX15 2682/4885
US-20210128735-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES LNPEP, PAICS, CD47 CYP2D6 4321/4885CYP1A2 4652/4885ALOX15 3243/4885
US-20200283560-A1 New polymer materials for contact lens applications CRYAA, CRYAB, BCAT1 CYP2D6 4570/4885CYP1A2 4572/4885ALOX15 2629/4885
US-11008414-B2 Polymer materials for contact lens applications CRYAA, BCAT1, CRYAB CYP2D6 4360/4885CYP1A2 4487/4885ALOX15 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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