SCHEMBL2044667

SCHEMBL2044667

CC(=O)ON=C1CCCC(=NOC(C)=O)C1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
MEN1 O00255 1/20 0.37
FAAH O00519 1/20 0.37
ABHD16A O95870 1/20 0.37
KMT2A Q03164 1/20 0.37
PLA2G7 Q13093 1/20 0.37
NCEH1 Q6PIU2 1/20 0.37
DAGLB Q8NCG7 1/20 0.37
DAGLA Q9Y4D2 1/20 0.37
GAA P10253 1/20 0.36
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044665 1.00 RAB9A (0.38) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL9898971 0.88 GAA (0.39) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL9898970 0.88 GAA (0.39) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL212464 0.86 RAB9A (0.47) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL2046021 0.86 ALDH1A1 (0.32) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL214510 0.84 MEN1 (0.50) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL212465 0.84 MEN1 (0.50) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL215531 0.84 MEN1 (0.50) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL212565 0.84 MEN1 (0.50) RAB9ASMN1; SMN2NPC1MEN1FAAH
SCHEMBL213364 0.84 MEN1 (0.50) RAB9ASMN1; SMN2NPC1MEN1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed