Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674771 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL20446680 | 0.98 | MAPT (0.36) | SMN1; SMN2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL1674813 | 0.98 | MAPT (0.36) | SMN1; SMN2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL1674777 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL1674774 | 0.80 | MAPT (0.36) | SMN1; SMN2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL15070197 | 0.69 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL13721802 | 0.61 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL9934710 | 0.61 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL6129223 | 0.59 | MAPT (0.44) | SMN1; SMN2MAPTHPGDALDH1A1LMNA | |
| SCHEMBL24415343 | 0.59 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |