Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355332 | 0.84 | MAPT (0.50) | MAPTHPGDALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL11934162 | 0.77 | MAOA (0.43) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28334942 | 0.74 | MAOA (0.41) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28279025 | 0.74 | MAOA (0.41) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27742309 | 0.74 | MAOA (0.41) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27621718 | 0.74 | MAOA (0.41) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| Hydrazine SCHEMBL27467817 | 0.73 | MAOA (0.40) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| Zinc Ion SCHEMBL27762063 | 0.73 | MAOA (0.40) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL120459 | 0.71 | SMN1; SMN2 (0.40) | MAPTHPGDALDH1A1NPC1RAB9A | |
| Benzene SCHEMBL28318743 | 0.71 | BRD4 (0.40) | MAPTHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050000529-A1 | Method and compositions for imparting cooling effect to tobacco products | VECTOR TOBACCO INC. | 2005-01-06 | — | — | US | claimed |
| EP-1455609-A2 | METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS | Vector Tobacco Inc. (US) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053176-A2 | METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS | VECTOR TOBACCO INC. (US) | 2003-07-03 | — | — | WO | claimed |
| US-20050000529-A1 | Method and compositions for imparting cooling effect to tobacco products | VECTOR TOBACCO INC. | 2005-01-06 | — | — | US | disclosed |