SCHEMBL1674777

SCHEMBL1674777

CC1(O)CC(N2CCCCC2)=C(O)C1=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ALDH1A1 P00352 4/20 0.33
LMNA P02545 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1674774 0.98 MAPT (0.36) SMN1; SMN2MAPTHPGDALDH1A1LMNA
SCHEMBL15070197 0.84 SMN1; SMN2 (0.39) SMN1; SMN2MAPTHPGDALDH1A1LMNA
SCHEMBL1674771 0.82 SMN1; SMN2 (0.38) SMN1; SMN2MAPTHPGDALDH1A1LMNA
SCHEMBL20446705 0.82 SMN1; SMN2 (0.38) SMN1; SMN2MAPTHPGDALDH1A1LMNA
SCHEMBL20446680 0.80 MAPT (0.36) SMN1; SMN2MAPTHPGDALDH1A1LMNA
SCHEMBL1674813 0.80 MAPT (0.36) SMN1; SMN2MAPTHPGDALDH1A1LMNA
SCHEMBL13721802 0.75 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL16886913 0.66 LMNA (0.30) MAPTALDH1A1LMNA
SCHEMBL17548917 0.65
SCHEMBL3458804 0.62 SMN1; SMN2 (0.39) SMN1; SMN2MAPTALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2661266-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES Elcelyx Therapeutics, Inc. (US) 2013-11-13 EP claimed
WO-2012094636-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-07-12 WO claimed
US-5773208-A MIXTURE WITH TETRAAZAINDENE COMPOUND EASTMAN KODAK COMPANY (US) 1998-06-30 US claimed
US-5691127-A SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1997-11-25 US claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
US-20230244134-A1 Photographic Paper FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2023-08-03 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 US disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
EP-0606895-A1 Photographic emulsions containing internally and externally modified silver halide grains EASTMAN KODAK COMPANY (US) 1994-07-20 EP disclosed
EP-0600564-A1 Method of photographic processing KODAK LIMITED (GB) 1994-06-08 EP disclosed
US-5260184-A Oxidatt removal by electrolysis at cathode, dialysis through semipermeable membrane, catalytic decomposition or by scavengers EASTMAN KODAK COMPANY (US) 1993-11-09 US disclosed
US-5256530-A Transition metal complexes EASTMAN KODAK COMPANY (US) 1993-10-26 US disclosed
US-5252451-A Comprising the transition metal complexes of a dopant and a grain surface modifier; high contrast EASTMAN KODAK COMPANY (US) 1993-10-12 US disclosed
EP-0469046-B1 METHOD OF FORMING A PHOTOGRAPHIC COLOUR IMAGE KODAK LIMITED (GB) 1993-03-31 EP disclosed
EP-0469046-A1 METHOD OF FORMING A PHOTOGRAPHIC COLOUR IMAGE. KODAK LTD (GB) 1992-02-05 EP disclosed
WO-1990013061-A1 METHOD OF FORMING A PHOTOGRAPHIC COLOUR IMAGE KODAK LIMITED (GB) 1990-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 SMN1; SMN2 1778/4885MAPT 4340/4885HPGD 1096/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 SMN1; SMN2 1778/4885MAPT 4340/4885HPGD 1096/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 SMN1; SMN2 1778/4885MAPT 4340/4885HPGD 1096/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 SMN1; SMN2 1778/4885MAPT 4340/4885HPGD 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.