SCHEMBL2044949

SCHEMBL2044949

C=CCC(C/C=C/C)(C(=O)NCc1ccccc1)C(=O)NCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.48
MMP8 P22894 3/20 0.44
OPRK1 P41145 1/20 0.42
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HDAC3 O15379 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EPHX2 P34913 3/20 0.40
CYP2C9 P11712 1/20 0.40
FAAH O00519 1/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044951 1.00 RIPK1 (0.48) RIPK1MMP8OPRK1GAASMN1; SMN2
SCHEMBL2047137 0.92 RIPK1 (0.44) RIPK1MMP8OPRK1GAASMN1; SMN2
SCHEMBL2047140 0.92 RIPK1 (0.44) RIPK1MMP8OPRK1GAASMN1; SMN2
SCHEMBL2051147 0.90 RIPK1 (0.53) RIPK1MMP8OPRK1GAASMN1; SMN2
SCHEMBL2044492 0.82 HTT (0.49) RIPK1MMP8OPRK1GAASMN1; SMN2
SCHEMBL2043286 0.81 TGM2 (0.42) MMP8MEN1KMT2AALDH1A1
SCHEMBL2043287 0.81 TGM2 (0.42) MMP8MEN1KMT2AALDH1A1
SCHEMBL4251588 0.81 EPHX2 (0.52) RIPK1MMP8GAAMEN1KMT2A
SCHEMBL4068358 0.77 EPHX2 (0.48) RIPK1MMP8GAAMEN1KMT2A
SCHEMBL4068361 0.77 EPHX2 (0.48) RIPK1MMP8GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
US-20080214754-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed