⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL28329676 | 0.78 | — | — | |
| Guanidine SCHEMBL3878080 | 0.76 | — | — | |
| Guanidine SCHEMBL8781874 | 0.73 | — | — | |
| Guanidine SCHEMBL11609229 | 0.73 | — | — | |
| Guanidine SCHEMBL5708316 | 0.73 | CA1 (0.31) | — | |
| SCHEMBL18436231 | 0.72 | — | — | |
| Guanidine SCHEMBL3753038 | 0.70 | — | — | |
| Guanidine SCHEMBL22468088 | 0.70 | ALDH1A1 (0.60) | — | |
| Guanidine SCHEMBL23069845 | 0.70 | CA1 (0.50) | — | |
| Guanidine SCHEMBL10886720 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013214-B1 | CONSTRAINED COMPOUNDS AS CGRP-RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2015-06-24 | — | — | EP | claimed |
| US-8859209-B2 | Reimmunization and antibody design | CARVIAR APS (DK) | 2014-10-14 | — | — | US | claimed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | claimed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | claimed |
| EP-2013213-B1 | CONSTRAINED COMPOUNDS AS CGRP-RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2011-07-27 | — | — | EP | claimed |
| US-20100143329-A1 | REIMMUNIZATION AND ANTIBODY DESIGN | CARVIAR APS (DK) | 2010-06-10 | — | — | US | claimed |
| US-20100081610-A1 | MATRIX METALLOPROTEINASE INHIBITORS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2010-04-01 | — | — | US | claimed |
| US-20090238816-A1 | METHOD FOR IMMUNIZING AN AVIAN SPECIES | THE ANTIBODY PROJECT APS (DK) | 2009-09-24 | — | — | US | claimed |
| US-7544680-B2 | Constrained compounds as CGRP-receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-09 | — | — | US | claimed |
| EP-2027158-A1 | METHOD FOR IMMUNIZING AN AVIAN SPECIES | The Antibody Project APS (DK) | 2009-02-25 | — | — | EP | claimed |
| US-5508426-A | ANTIARTHRITIC AGENT | G. D. SEARLE & CO. (US) | 1996-04-16 | — | — | US | claimed |
| US-5504215-A | Substituted pyrazolyl benzenesulfonamide compounds for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | claimed |
| WO-1996009293-A1 | BENZ[g]INDAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |
| WO-1995015316-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G. D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | claimed |
| EP-0012112-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | claimed |
| US-4291901-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1981-09-29 | — | — | US | claimed |
| EP-0012112-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | claimed |
| WO-1979000166-A1 | CYANOCARBOXAMIDINES AND QUINAZOLINE PROCESS | BRISTOL MYERS CO (US) | 1979-04-05 | — | — | WO | claimed |
| US-4138561-A | Cyanocarboxamidines and quinazoline process | BRISTOL-MYERS COMPANY (US) | 1979-02-06 | — | — | US | claimed |