Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL28036077 | 0.88 | MAPK1 (0.33) | — | |
| Guanidine SCHEMBL5708316 | 0.86 | CA1 (0.31) | — | |
| Guanidine SCHEMBL8781874 | 0.86 | — | — | |
| Guanidine SCHEMBL11609229 | 0.86 | — | — | |
| Guanidine SCHEMBL66976 | 0.84 | — | — | |
| Guanidine SCHEMBL30875702 | 0.84 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL28214584 | 0.84 | — | — | |
| Guanidine SCHEMBL20138497 | 0.84 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL66977 | 0.84 | — | — | |
| Guanidine SCHEMBL23069845 | 0.82 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762210-B | 2-Aldoxime-5-fluoropyrimidine derivatives | DOW AGROSCIENCES LLC | 2014-09-17 | — | — | CN | disclosed |
| CN-102771495-B | Pesticide synergic insect-killing composition containing guadipyr | HENAN JINTIANDI AGROCHEMICAL CO LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-102771495-A | Pesticide synergic insect-killing composition containing guadipyr | HENAN JINTIANDI AGROCHEMICAL CO LTD | 2012-11-14 | — | — | CN | disclosed |
| US-7531112-B2 | Composition for forming dielectric, capacitor produced using composition, and printed circuit board provided with capacitor | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2009-05-12 | — | — | US | disclosed |
| US-20070027246-A1 | Composition for forming dielectric, capacitor produced using composition, and printed circuit board provided with capacitor | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2007-02-01 | — | — | US | disclosed |