Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.43 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.43 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512989 | 0.98 | MEN1 (0.56) | MEN1CYP2C19KMT2ATSHRKCNA4 | |
| SCHEMBL11515285 | 0.98 | MEN1 (0.56) | MEN1CYP2C19KMT2ATSHRKCNA4 | |
| SCHEMBL733501 | 0.95 | CYP2C19 (0.58) | MEN1CYP2C19KMT2ATSHRKCNA4 | |
| SCHEMBL366283 | 0.90 | CYP2C19 (0.62) | MEN1CYP2C19KMT2ATSHRKCNA4 | |
| Biphenyl SCHEMBL28725381 | 0.83 | MEN1 (0.56) | MEN1CYP2C19KMT2ATSHRKCNA4 | |
| SCHEMBL24109360 | 0.82 | MEN1 (0.45) | MEN1CYP2C19KMT2A | |
| SCHEMBL23483030 | 0.82 | MEN1 (0.45) | MEN1CYP2C19KMT2A | |
| SCHEMBL17818440 | 0.82 | MEN1 (0.42) | MEN1CYP2C19KMT2ATSHRL3MBTL1 | |
| SCHEMBL9451018 | 0.81 | MEN1 (0.41) | MEN1CYP2C19KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5946282 | 0.79 | CYP2C19 (0.62) | MEN1CYP2C19KMT2ATSHRKCNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180646-A | BIOERODABLE SUSTAINED RELEASE COTAINGS | ALZA CORPORATION (US) | 1979-12-25 | — | — | US | claimed |
| US-8629268-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-01-14 | — | — | US | disclosed |
| CN-103012628-A | Solid catalyst for olefin polymerization and process for producing olefin polymer | SUMITOMO CHEMICAL CO | 2013-04-03 | — | — | CN | disclosed |
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-02-21 | — | — | US | disclosed |
| US-8227645-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-07-24 | — | — | US | disclosed |
| US-7956132-B2 | Production of telechelic compounds by metathesis depolymerization | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-06-07 | — | — | US | disclosed |
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-09-09 | — | — | US | disclosed |
| US-20100168352-A1 | PRODUCTION OF TELECHELIC COMPOUNDS BY METATHESIS DEPOLYMERIZATION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-01 | — | — | US | disclosed |
| EP-2057196-B1 | PRODUCTION OF TELECHELIC COMPOUNDS BY METATHESIS DEPOLYMERIZATION | DOW GLOBAL TECHNOLOGIES INC (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-2057196-A2 | PRODUCTION OF TELECHELIC COMPOUNDS BY METATHESIS DEPOLYMERIZATION | Dow Global Technologies Inc. (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2009009158-A2 | METATHETIC PRODUCTION OF FUNCTIONALIZED POLYMERS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2009-01-15 | — | — | WO | disclosed |
| WO-2008027269-A2 | PRODUCTION OF TELECHELIC COMPOUNDS BY METATHESIS DEPOLYMERIZATION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2007097719-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2007-08-30 | — | — | WO | disclosed |
| US-20060178493-A1 | Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-08-10 | — | — | US | disclosed |
| US-7022789-B2 | Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-04 | — | — | US | disclosed |
| US-20050176906-A1 | Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-08-11 | — | — | US | disclosed |
| US-6867274-B2 | Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020169263-A1 | Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-11-14 | — | — | US | disclosed |
| US-6465590-B1 | FROM REACTION OF A FUNCTIONALIZED CHAIN TRANSFER AGENT HAVING CROSSLINKABLE ENDS WITH A CYCLOALKENE | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | DHPS, GGPS1, COASY | MEN1 458/4885CYP2C19 215/4885KMT2A 2281/4885 |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | COASY, AKR1C4, AKR1C2 | MEN1 541/4885CYP2C19 230/4885KMT2A 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.