SCHEMBL366283

SCHEMBL366283

c1ccc(C2OCCO2)cc1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
TSHR P16473 1/20 0.52
KCNA4 P22459 1/20 0.46
KCNA1 Q09470 1/20 0.46
KCNAB1 Q14722 1/20 0.46
SLC6A2 P23975 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HTR1A P08908 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28725381 0.93 MEN1 (0.56) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL2045490 0.90 MEN1 (0.58) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL733501 0.90 CYP2C19 (0.58) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL11515285 0.87 MEN1 (0.56) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL11512989 0.87 MEN1 (0.56) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL3597677 0.85 MEN1 (0.48) CYP2C19MEN1KMT2ATSHR
SCHEMBL9451016 0.85 MEN1 (0.44) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL5946282 0.83 CYP2C19 (0.62) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL16884712 0.80 MEN1 (0.44) CYP2C19MEN1KMT2ATSHRKCNA4
SCHEMBL1106845 0.80 CHRM2 (0.44) CYP2C19MEN1KMT2ATSHRKCNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024032715-A1 HYDRAZIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳微芯生物科技股份有限公司 2024-02-15 WO claimed
CN-116730995-A Hydrazide compound, preparation method and application thereof 深圳微芯生物科技股份有限公司 2023-09-12 CN claimed
CN-116410374-A Star-branched telechelic polyisobutene, and preparation method and application thereof 北京石油化工学院 2023-07-11 CN claimed
WO-2023064195-A1 CGRP ANTAGONISTS FOR TREATING TRIGEMINAL NEURALGIA PFIZER IRELAND PHARMACEUTICALS (IE) 2023-04-20 WO claimed
WO-2023034467-A2 CGRP ANTAGONISTS FOR TREATING SKIN CONDITIONS PFIZER IRELAND PHARMACEUTICALS (IE) 2023-03-09 WO claimed
WO-2023034466-A1 CGRP ANTAGONISTS FOR TREATING PSORIASIS PFIZER IRELAND PHARMACEUTICALS (IE) 2023-03-09 WO claimed
US-10669250-B2 Hypervalent iodine CF2CF2X reagents and their use ETH ZURICH (CH) 2020-06-02 US claimed
CN-110343109-A A kind of dihydro pteridinone-sulfonic acid amide derivatives and its pharmaceutically acceptable salt, preparation method and its application 郑州大学 2019-10-18 CN claimed
US-20190040036-A1 HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE ETH ZURICH (CH) 2019-02-07 US claimed
CN-108129462-A A kind of dioxolanyl benzimidazole compound and preparation method thereof 广东工业大学 2018-06-08 CN claimed
EP-0428849-A2 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-29 EP claimed
EP-0400779-A1 Biological production of novel cyclohexadienediols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP claimed
EP-0370454-A2 Renin-inhibiting amino diol derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0177913-B1 CYCLOHEXENONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-01-03 EP claimed
US-4624696-A Cyclohexenone derivatives and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1986-11-25 US claimed
EP-0177913-A1 Cyclohexenone derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1986-04-16 EP claimed
EP-0014928-B1 PIPERIDINOPROPYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1982-05-05 EP claimed
US-4304921-A Method of preparing β-halo esters from cyclic acetals VANDERBILT UNIVERSITY (US) 1981-12-08 US claimed
US-4192720-A Electrodeposition process for forming amorphous silicon EXXON RESEARCH & ENGINEERING CO. (US) 1980-03-11 US claimed
US-4180646-A BIOERODABLE SUSTAINED RELEASE COTAINGS ALZA CORPORATION (US) 1979-12-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10669250-B2 Hypervalent iodine CF2CF2X reagents and their use TPO, FANCF, FANCI CYP2C19 2850/4885MEN1 220/4885KMT2A 741/4885
US-20190040036-A1 HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE TPO, FANCF, FANCI CYP2C19 2850/4885MEN1 220/4885KMT2A 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.