Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233849 | 0.79 | LMNA (0.31) | LMNA | |
| SCHEMBL15306036 | 0.71 | LMNA (0.32) | LMNA | |
| SCHEMBL12351996 | 0.70 | LMNA (0.33) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL20458721 | 0.70 | HTT (0.34) | LMNAHTT | |
| SCHEMBL2234253 | 0.67 | LTA4H (0.39) | HTTSMN1; SMN2 | |
| SCHEMBL2236713 | 0.67 | TYR (0.35) | LMNAALDH1A1KDM4E | |
| SCHEMBL15305976 | 0.67 | TYR (0.35) | LMNAALDH1A1KDM4E | |
| SCHEMBL2235262 | 0.67 | TYR (0.35) | LMNAALDH1A1KDM4E | |
| SCHEMBL20458743 | 0.66 | KCNH2 (0.34) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2232923 | 0.65 | TYR (0.33) | LMNAALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536690-B1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | UNIV ARIZONA (US) | 2018-08-08 | — | — | EP | disclosed |