Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 6/20 | 0.46 |
| ▸ | PPP5C | P53041 | 2/20 | 0.40 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880144 | 0.83 | TFPI2 (0.45) | TFPI2PPP5CPPP2CANPY4RCHRNB2 | |
| SCHEMBL21360341 | 0.83 | TFPI2 (0.45) | TFPI2PPP5CPPP2CANPY4RCHRNB2 | |
| SCHEMBL19388110 | 0.79 | TFPI2 (0.45) | TFPI2PPP5CPPM1B | |
| SCHEMBL9880150 | 0.75 | TFPI2 (0.73) | TFPI2PPP5CPPP2CANPY4RCHRNB2 | |
| SCHEMBL2334396 | 0.75 | TFPI2 (0.73) | TFPI2PPP5CPPP2CANPY4RCHRNB2 | |
| SCHEMBL13311572 | 0.75 | TFPI2 (0.73) | TFPI2PPP5CPPP2CANPY4RCHRNB2 | |
| SCHEMBL13001974 | 0.70 | CHRNB2 (0.43) | TFPI2PPP5CPPP2CANPY4RCHRNB2 | |
| SCHEMBL2330162 | 0.70 | TFPI2 (0.55) | TFPI2PPP5CPPP2CANPY4RCHRNB2 | |
| SCHEMBL9880141 | 0.67 | TFPI2 (0.56) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL19177682 | 0.67 | TSHR (0.40) | TFPI2CHRNB2CHRNA3CHRNA4CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870161-B1 | OXABICYCLOHEPTANES AND OXABICYCLOHEPTENES FOR THE TREATMENT OF REPERFUSION INJURY | LIXTE BIOTECHNOLOGY INC (US) | 2018-08-08 | — | — | EP | disclosed |