Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192980 | 1.00 | ABL1 (0.34) | ABL1RIN1POLBMAPTNT5E | |
| SCHEMBL15702102 | 1.00 | ABL1 (0.34) | ABL1RIN1POLBMAPTNT5E | |
| SCHEMBL15765636 | 0.91 | MAPT (0.33) | ABL1RIN1POLBMAPTP2RY6 | |
| SCHEMBL15702099 | 0.91 | MAPT (0.33) | ABL1RIN1POLBMAPTP2RY6 | |
| SCHEMBL13672345 | 0.90 | ABL1 (0.47) | ABL1RIN1POLBMAPTNT5E | |
| SCHEMBL12452563 | 0.90 | ABL1 (0.47) | ABL1RIN1POLBMAPTNT5E | |
| SCHEMBL17832132 | 0.84 | POLB (0.37) | ABL1RIN1POLBMAPTNT5E | |
| SCHEMBL20215740 | 0.83 | P2RY6 (0.34) | ABL1RIN1POLBMAPTNT5E | |
| SCHEMBL20459987 | 0.83 | P2RY6 (0.34) | ABL1RIN1POLBMAPTNT5E | |
| SCHEMBL19981007 | 0.83 | P2RY6 (0.34) | ABL1RIN1POLBMAPTNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424510-A1 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF 2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYLCYTOSINE | Cyclacel Limited (GB) | 2019-01-09 | — | — | EP | disclosed |
| EP-2291193-B1 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF 2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYLCYTOSINE | CYCLACEL LTD (GB) | 2018-08-08 | — | — | EP | disclosed |