Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 5/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937265 | 1.00 | P2RY6 (0.34) | P2RY6P2RY14NT5EMAPTROCK2 | |
| SCHEMBL19981007 | 1.00 | P2RY6 (0.34) | P2RY6P2RY14NT5EMAPTROCK2 | |
| SCHEMBL14946367 | 1.00 | P2RY6 (0.34) | P2RY6P2RY14NT5EMAPTROCK2 | |
| SCHEMBL10459464 | 1.00 | P2RY6 (0.34) | P2RY6P2RY14NT5EMAPTROCK2 | |
| SCHEMBL20215740 | 1.00 | P2RY6 (0.34) | P2RY6P2RY14NT5EMAPTROCK2 | |
| SCHEMBL14946314 | 0.92 | MAPT (0.32) | P2RY6P2RY14NT5EMAPTROCK2 | |
| SCHEMBL16229229 | 0.89 | MAPT (0.31) | MAPTABL1RIN1 | |
| SCHEMBL13151571 | 0.89 | P2RY6 (0.47) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL6365808 | 0.89 | P2RY6 (0.47) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL13672352 | 0.89 | P2RY6 (0.47) | P2RY6P2RY14NT5EP2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291193-B1 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF 2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYLCYTOSINE | CYCLACEL LTD (GB) | 2018-08-08 | — | — | EP | disclosed |