Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 2/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250777 | 0.85 | MAPT (0.32) | MAPT | |
| SCHEMBL14946367 | 0.84 | P2RY6 (0.34) | POLBABL1RIN1MAPTROCK2 | |
| SCHEMBL10459464 | 0.84 | P2RY6 (0.34) | POLBABL1RIN1MAPTROCK2 | |
| SCHEMBL1937265 | 0.84 | P2RY6 (0.34) | POLBABL1RIN1MAPTROCK2 | |
| SCHEMBL20215740 | 0.84 | P2RY6 (0.34) | POLBABL1RIN1MAPTROCK2 | |
| SCHEMBL19981007 | 0.84 | P2RY6 (0.34) | POLBABL1RIN1MAPTROCK2 | |
| SCHEMBL20459987 | 0.84 | P2RY6 (0.34) | POLBABL1RIN1MAPTROCK2 | |
| SCHEMBL17192980 | 0.84 | ABL1 (0.34) | POLBABL1RIN1MAPTNT5E | |
| SCHEMBL20459893 | 0.84 | ABL1 (0.34) | POLBABL1RIN1MAPTNT5E | |
| SCHEMBL14946314 | 0.84 | MAPT (0.32) | POLBABL1RIN1MAPTROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094677-A2 | MONONUCLEOTIDES HAVING A BIOREVERSIBLE DISULFIDE GROUP | SOLSTICE BIOLOGICS, LTD. (IE) | 2016-06-16 | — | — | WO | disclosed |