Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20460460 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL4826908 | 0.74 | CYP1A2 (0.55) | SMN1; SMN2LMNAHTTALDH1A1MEN1 | |
| SCHEMBL12190515 | 0.74 | ALDH1A1 (0.52) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL25494287 | 0.73 | TP53 (0.44) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL6197998 | 0.72 | LMNA (0.49) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL4826373 | 0.71 | CYP1A2 (0.55) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL4821297 | 0.71 | CYP1A2 (0.55) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 | |
| SCHEMBL4820272 | 0.71 | CYP1A2 (0.55) | SMN1; SMN2LMNAHTTALDH1A1MEN1 | |
| SCHEMBL9979294 | 0.71 | MAPT (0.52) | LMNAHTTMEN1KMT2ACYP1A2 | |
| SCHEMBL18615673 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2LMNAHTTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357916-A1 | BENZAMIDE DERIVATIVE | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2018-08-08 | — | — | EP | disclosed |