Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTAFR | P25105 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130980 | 0.98 | POLB (0.62) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16907559 | 0.93 | PDK2 (0.58) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9001766 | 0.91 | ALDH1A1 (0.66) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8366263 | 0.85 | MEN1 (0.55) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10195018 | 0.85 | PDK2 (0.52) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20460528 | 0.84 | ALDH1A1 (0.56) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4488042 | 0.84 | ALDH1A1 (0.59) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4359670 | 0.84 | HPGD (0.59) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12082859 | 0.83 | PDK2 (0.61) | PDK2LMNA | |
| SCHEMBL14297351 | 0.83 | PDK2 (0.45) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357916-A1 | BENZAMIDE DERIVATIVE | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2018-08-08 | — | — | EP | disclosed |