Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16907559 | 0.88 | PDK2 (0.58) | MEN1KMT2APDK2NPC1POLB | |
| SCHEMBL28630966 | 0.87 | POLB (0.46) | MEN1KMT2ACYP2D6PDK2SLC6A4 | |
| SCHEMBL28646233 | 0.86 | CCR5 (0.51) | PDK2SLC6A4MCHR1ALDH1A1GAA | |
| SCHEMBL3809371 | 0.85 | SLC6A4 (0.51) | SLC6A4OPRD1HPGDSLC6A2KCNH2 | |
| SCHEMBL20460529 | 0.85 | POLB (0.60) | MEN1KMT2APDK2NPC1POLB | |
| Hydrochloric Acid SCHEMBL19520331 | 0.84 | L3MBTL1 (0.58) | MEN1KMT2ACYP2D6PDK2SLC6A4 | |
| SCHEMBL8130980 | 0.83 | POLB (0.62) | MEN1KMT2APDK2NPC1POLB | |
| SCHEMBL16578992 | 0.83 | EGLN1 (0.50) | PDK2SLC6A4SLC6A2 | |
| SCHEMBL28628582 | 0.83 | MCHR1 (0.50) | MEN1KMT2ASLC6A4NPC1RAB9A | |
| SCHEMBL17572927 | 0.83 | SMN1; SMN2 (0.44) | MEN1KMT2APDK2SLC6A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293771-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | HRH4, HRH3, HRH2 | MEN1 1509/4885KMT2A 236/4885CYP2D6 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.