SCHEMBL2046124

SCHEMBL2046124

Cc1ccc(N(c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.59
CYP19A1 P11511 2/20 0.49
CYP11B2 P19099 2/20 0.49
ESR1 P03372 2/20 0.46
TRPM8 Q7Z2W7 1/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 4/20 0.44
HPGD P15428 2/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP2D6 P10635 1/20 0.42
ESR2 Q92731 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85628 1.00 PTGS2 (0.59) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL5937761 0.98 PTGS2 (0.61) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL14526458 0.98 PTGS2 (0.61) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL12763721 0.98 PTGS2 (0.61) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL12009443 0.98 PTGS2 (0.57) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL14570428 0.98 PTGS2 (0.61) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL14526457 0.98 PTGS2 (0.61) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL18745204 0.97 PTGS2 (0.60) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL9887485 0.97 PTGS2 (0.60) PTGS2CYP19A1CYP11B2ESR1TRPM8
SCHEMBL13899091 0.97 PTGS2 (0.60) PTGS2CYP19A1CYP11B2ESR1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141546-B1 Photoconductors containing Tris and Bis(enylaryl)arylamine XEROX CORP (US) 2013-05-22 EP claimed
US-20120208116-A1 BIS(ENYLARYL)ARYLAMINE CHARGE TRANSPORT LAYER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2012-08-16 US claimed
US-7981580-B2 Tris and bis(enylaryl)arylamine mixtures containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7968262-B2 Bis(enylaryl)arylamine containing photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
EP-2141546-A1 Photoconductors containing Tris and Bis(enylaryl)arylamine Xerox Corporation (US) 2010-01-06 EP claimed
US-20090325092-A1 BIS(ENYLARYL)ARYLAMINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-20090325095-A1 TRIS AND BIS(ENYLARYL)ARYLAMINE MIXTURES CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-11586119-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2023-02-21 US disclosed
US-11143976-B2 Photoconductor having interlayer for hole injection promotion FUJI ELECTRIC CO., LTD. (JP) 2021-10-12 US disclosed
US-11036151-B2 Electrophotographic photoreceptor, method for manufacturing same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2021-06-15 US disclosed
US-20210124279-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF MANUFACTURING THE PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2021-04-29 US disclosed
US-10962893-B2 Photosensitive body for electrophotography, method for producing same and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2021-03-30 US disclosed
US-10802411-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-10-13 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080153019-A1 ARYLAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJIFILM FINECHEMICALS CO., LTD. (JP) 2008-06-26 US disclosed
US-20080153019-A1 ARYLAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJIFILM FINECHEMICALS CO., LTD. (JP) 2008-06-26 US disclosed
EP-1921500-A1 UV-sensitive elements with triarylamine derivatives as sensitizers EASTMAN KODAK COMPANY (US) 2008-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153019-A1 ARYLAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR NR2E3, ARRB1, ALDH1A2 PTGS2 3231/4885CYP19A1 1943/4885CYP11B2 877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.