Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRY1 | Q16526 | 20/20 | 0.75 |
| ▸ | CRY2 | Q49AN0 | 20/20 | 0.75 |
| ▸ | PER2 | O15055 | 19/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20462166 | 0.96 | PER2 (0.74) | CRY1CRY2PER2 | |
| SCHEMBL15379687 | 0.86 | CRY1 (1.00) | CRY1CRY2PER2 | |
| SCHEMBL15380100 | 0.81 | CRY1 (1.00) | CRY1CRY2PER2 | |
| SCHEMBL20462161 | 0.81 | CRY1 (0.72) | CRY1CRY2PER2 | |
| SCHEMBL20462260 | 0.79 | CRY1 (0.74) | CRY1CRY2PER2 | |
| SCHEMBL20462165 | 0.77 | CRY1 (0.75) | CRY1CRY2PER2 | |
| SCHEMBL20462277 | 0.74 | CRY1 (0.51) | CRY1CRY2PER2 | |
| SCHEMBL15380551 | 0.74 | PER2 (1.00) | CRY1CRY2PER2 | |
| SCHEMBL20462295 | 0.73 | CRY1 (0.51) | CRY1CRY2PER2 | |
| SCHEMBL15383987 | 0.73 | PER2 (0.70) | CRY1CRY2PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855458-B1 | CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS | RESET THERAPEUTICS INC (US) | 2018-08-08 | — | — | EP | disclosed |