Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367427 | 0.90 | HRH3 (0.44) | HRH3MAOAMAOB | |
| SCHEMBL21477175 | 0.80 | MAOA (0.40) | HRH3MAOAMAOBDRD2 | |
| SCHEMBL30479975 | 0.78 | AR (0.51) | — | |
| SCHEMBL20423483 | 0.78 | AR (0.51) | — | |
| SCHEMBL20423484 | 0.78 | AR (0.51) | — | |
| SCHEMBL20423116 | 0.77 | CRBN (0.44) | HRH3 | |
| SCHEMBL20423470 | 0.77 | CRBN (0.46) | HRH3 | |
| SCHEMBL20463105 | 0.73 | CRBN (0.44) | HRH3MAOAMAOBDRD2 | |
| SCHEMBL21480831 | 0.73 | MAOA (0.48) | MAOAMAOBDRD2 | |
| SCHEMBL21477172 | 0.71 | MAOA (0.42) | MAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144649-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | Arvinas, Inc. (US) | 2018-08-09 | — | — | WO | disclosed |