Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20436992 | 0.75 | CYP4F2 (0.37) | NPBWR1MCHR1ATMLMNA | |
| SCHEMBL15566368 | 0.63 | SMN1; SMN2 (0.56) | NPBWR1MCHR1ATMLMNASMN1; SMN2 | |
| SCHEMBL10919469 | 0.59 | CYSLTR1 (0.42) | — | |
| SCHEMBL1629691 | 0.58 | SMN1; SMN2 (0.44) | ATMLMNASMN1; SMN2 | |
| SCHEMBL20436993 | 0.58 | ESR1 (0.43) | ATMSMN1; SMN2 | |
| SCHEMBL19260302 | 0.57 | KDM4E (0.35) | SMN1; SMN2 | |
| SCHEMBL3409477 | 0.57 | SMN1; SMN2 (0.45) | NPBWR1MCHR1ATMLMNASMN1; SMN2 | |
| SCHEMBL20099862 | 0.57 | PDE10A (0.42) | SMN1; SMN2 | |
| SCHEMBL3547047 | 0.57 | ADRA2A (0.40) | SMN1; SMN2 | |
| SCHEMBL4768617 | 0.57 | ADRA2A (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144649-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | Arvinas, Inc. (US) | 2018-08-09 | — | — | WO | disclosed |