Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743759 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8810970 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL29951519 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL19606333 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL9636118 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL19816502 | 1.00 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14590766 | 0.98 | HIF1A (0.65) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL293574 | 0.91 | — | — | |
| Methoxymethane SCHEMBL29037433 | 0.85 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL23442125 | 0.84 | KDM4E (0.73) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611254-B1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF HEXAMETHYLENEDIAMINE | GENOMATICA INC (US) | 2023-07-05 | — | — | EP | claimed |
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-12577594-B2 | Engineered microorganisms and methods for improved aldehyde dehydrogenase activity | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20260028651-A1 | METHOD OF PRODUCING & PROCESSING DIAMINES | AGAIN BIO APS (DK) | 2026-01-29 | — | — | US | disclosed |
| US-12503711-B2 | Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism | GENOMATICA, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| EP-4642908-A2 | LIGASE AND DEHYDROGENASE VARIANTS AND METHODS OF USE | Genomatica, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20250305013-A1 | Methods and Compositions for Making Amide Compounds | GENOMATICA, INC. (US) | 2025-10-02 | — | — | US | disclosed |
| CN-114728871-B | Microorganisms and methods for reducing byproducts | 基因组股份公司 | 2024-12-27 | — | — | CN | disclosed |
| US-20240294885-A1 | ENGINEERED ENZYMES AND METHODS OF MAKING AND USING | AGAIN BIO APS (DK) | 2024-09-05 | — | — | US | disclosed |
| EP-4423259-A1 | ENGINEERED ENZYMES AND METHODS OF MAKING AND USING | Genomatica, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| US-20100317069-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2010-12-16 | — | — | US | disclosed |
| WO-2010129936-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | GENOMATICA, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| EP-2162435-A1 | IONIC LIQUIDS AS ELECTROLYTES | Invista Technologies S.A.R.L. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150842-A1 | IONIC LIQUIDS AS ELECTROLYTES | INVISTA TECHNOLOGIES S.A.R.L. (US) | 2008-12-11 | — | — | WO | disclosed |
| US-20080296531-A1 | IONIC LIQUIDS | INVISTA NORTH AMERICA S.A R.L. (US) | 2008-12-04 | — | — | US | disclosed |
| US-6974804-B2 | Esters | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| EP-0783479-B1 | CONVERSION OF NYLON 6 AND/OR NYLON 6,6 TO ADIPIC ACID | DU PONT (US) | 1999-10-06 | — | — | EP | disclosed |
| EP-0783479-A1 | CONVERSION OF NYLON 6 AND/OR NYLON 6,6 TO ADIPIC ACID | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010008-A1 | CONVERSION OF NYLON 6 AND/OR NYLON 6,6 TO ADIPIC ACID | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-04 | — | — | WO | disclosed |
| US-5468900-A | Conversion of nylon 6 and/or nylon 6,6 to adipic acid | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577594-B2 | Engineered microorganisms and methods for improved aldehyde dehydrogenase activity | ACADM, ALDH7A1, ADSL | KDM4E 543/4885MAPK1 4444/4885HIF1A 1689/4885 |
| US-20260028651-A1 | METHOD OF PRODUCING & PROCESSING DIAMINES | DDC, DAO, ODC1 | KDM4E 1463/4885MAPK1 2324/4885HIF1A 923/4885 |
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | ABAT, HADHB, MMAB | KDM4E 2135/4885MAPK1 4141/4885HIF1A 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.