Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 2/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | BAD | Q92934 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63466 | 0.93 | TSHR (0.70) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL27555709 | 0.93 | TSHR (0.70) | TSHRCA1CA2CA12CA9 | |
| Terephthalic Acid SCHEMBL4349174 | 0.93 | TSHR (0.70) | TSHRCA1CA2CA12CA9 | |
| Terephthalic Acid SCHEMBL8811649 | 0.93 | TSHR (0.70) | TSHRCA1CA2CA12CA9 | |
| Terephthalic Acid SCHEMBL18394717 | 0.93 | TSHR (0.70) | TSHRCA1CA2CA12CA9 | |
| Hydrochloric Acid SCHEMBL296016 | 0.91 | TSHR (0.67) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL11668494 | 0.91 | TSHR (0.67) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL2395112 | 0.91 | TSHR (0.67) | TSHRCA1CA2CA12CA9 | |
| Methyl Alcohol SCHEMBL29033870 | 0.91 | TSHR (0.67) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL27860895 | 0.91 | TSHR (0.67) | TSHRCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10036320-A | — | — | None | — | — | JP | disclosed |
| JP-9025257-A | — | — | None | — | — | JP | disclosed |
| JP-4029957-A | — | — | None | — | — | JP | disclosed |
| WO-2024098039-A2 | POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| CN-116867876-A | Anisotropic thermally conductive polymers and methods of making and using the same | HRL实验室有限责任公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-115124677-B | Meltable metallic organic framework material and covalent organic framework material, and preparation methods and uses thereof | 首都师范大学 | 2023-09-26 | — | — | CN | disclosed |
| US-20230143425-A1 | IMPROVEMENTS RELATED TO SORBENT MEDIA | GENESIS SYSTEMS LLC | 2023-05-11 | — | — | US | disclosed |
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |
| US-20220402947-A1 | Trialkyne Linking Agents and Methods of Use | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2022-12-22 | — | — | US | disclosed |
| CN-113621175-B | Efficient isotactic polypropylene beta-crystal form nucleating agent and preparation method and application thereof | 中国科学院化学研究所 | 2022-10-18 | — | — | CN | disclosed |
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | KATTAR SOLOMON | 2010-08-26 | — | — | US | disclosed |
| EP-2205070-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009045385-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| WO-2009045385-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| US-5898059-A | REACTING A DI(C1-C4)ALKYL TEREPHTHALATE WITH ETHYLENE GLYCOL TO YIELD BIS(2-HYDROXYETHYL) TEREPHTHALATE, ADDING A PHOSPHORUS SEQUESTERING AGENT AND POLYCONDENSING TO PRODUCE THE ARTICLES WITH LOW PARTICLE CONTENT, SMOOTH SURFACE | HOECHST DIAFOIL COMPANY (US) | 1999-04-27 | — | — | US | disclosed |
| EP-0864596-A1 | Process for the production of polyethylene terephthalate | Hoechst Diafoil GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |
| JP-H1036320-A | PRODUCTION OF 4,4'-DICYCLOHEXANEDICARBOXYLIC ACID DIMETHYL ESTER | TEIJIN LTD | 1998-02-10 | — | — | JP | disclosed |
| JP-H0925257-A | PRODUCTION OF POLYCYCLIC AROMATIC DICARBOXLIC ACID DIALKYLESTER | NIPPON STEEL CHEM CO LTD | 1997-01-28 | — | — | JP | disclosed |
| JP-H0429957-A | PRODUCTION OF BIARYL DERIVATIVE | IHARA CHEM IND CO LTD | 1992-01-31 | — | — | JP | disclosed |
| US-4613208-A | ELECTROOPTICS; ULTRAVIOLET RADIATION STABILITY; QUICK RESPONSE | HOFFMANN-LA ROCHE INC. (US) | 1986-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | BRDT, AADAC, ACIN1 | TSHR 2036/4885CA1 739/4885CA2 1352/4885 |
| US-20220402947-A1 | Trialkyne Linking Agents and Methods of Use | DCLRE1A, DTYMK, RTCB | TSHR 3215/4885CA1 4830/4885CA2 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.