Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456238 | 0.93 | PTGER4 (0.36) | KDM4EATML3MBTL1MAPTCYP1A2 | |
| SCHEMBL18456233 | 0.93 | MAPT (0.34) | KDM4EATML3MBTL1MAPTCYP1A2 | |
| SCHEMBL18455975 | 0.92 | CYP1A2 (0.39) | MAPTCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL21212864 | 0.91 | CYP1A2 (0.36) | KDM4EMAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18455574 | 0.90 | CYP1A2 (0.36) | MAPTCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL18456255 | 0.88 | MAPT (0.36) | KDM4EATML3MBTL1MAPTCYP1A2 | |
| SCHEMBL18455575 | 0.87 | TSHR (0.34) | MAPTCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL20465501 | 0.87 | PTGER4 (0.33) | MAPTCYP1A2CYP3A4CYP2D6HSD17B10 | |
| SCHEMBL18455502 | 0.85 | CYP1A2 (0.34) | MAPTCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL18455573 | 0.85 | CYP1A2 (0.32) | MAPTCYP1A2CYP3A4CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11201296-B2 | Compounds having fluorene structures | MERCK PATENT GMBH (DE) | 2021-12-14 | — | — | US | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | FSCN1, EFNA1, FLNA | KDM4E 3228/4885ATM 4239/4885L3MBTL1 4011/4885 |
| US-11201296-B2 | Compounds having fluorene structures | FSCN1, EFNA1, FLNA | KDM4E 3228/4885ATM 4239/4885L3MBTL1 4011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.