SCHEMBL20466268

SCHEMBL20466268

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nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.51
▸ THRB P10828 1/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bilobalide SCHEMBL19236272 0.68 KMT2A (1.00) MEN1THRBALOX15KMT2ASMN1; SMN2
Bilobalide SCHEMBL13960090 0.68 KMT2A (1.00) MEN1THRBALOX15KMT2ASMN1; SMN2
Bilobalide SCHEMBL16653675 0.68 KMT2A (1.00) MEN1THRBALOX15KMT2ASMN1; SMN2
Bilobalide SCHEMBL14029382 0.68 KMT2A (1.00) MEN1THRBALOX15KMT2ASMN1; SMN2
Bilobalide SCHEMBL18327718 0.68 KMT2A (1.00) MEN1THRBALOX15KMT2ASMN1; SMN2
SCHEMBL29974351 0.67 MEN1 (0.72) MEN1THRBALOX15KMT2ASMN1; SMN2
SCHEMBL31364706 0.66 MEN1 (0.65) MEN1THRBALOX15KMT2ASMN1; SMN2
SCHEMBL31364697 0.64 MEN1 (0.62) MEN1THRBALOX15KMT2ASMN1; SMN2
SCHEMBL31364726 0.64 MEN1 (0.47) MEN1THRBALOX15KMT2ASMN1; SMN2
SCHEMBL31364714 0.64 MEN1 (0.47) MEN1THRBALOX15KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10440953-B2 Control of pests in maize by ginkgolides and bilobalide BASF SE (DE) 2019-10-15 — — US disclosed
US-20180220656-A1 CONTROL OF PESTS IN MAIZE BY GINKGOLIDES AND BILOBALIDE BASF SE (DE) 2018-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10440953-B2 Control of pests in maize by ginkgolides and bilobalide GAK, AGL, BROX MEN1 475/4885THRB 3089/4885ALOX15 900/4885
US-20180220656-A1 CONTROL OF PESTS IN MAIZE BY GINKGOLIDES AND BILOBALIDE GAK, AGL, BROX MEN1 475/4885THRB 3089/4885ALOX15 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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