SCHEMBL204666

SCHEMBL204666

CCc1cccc(C)c1S(=O)(=O)c1ncn(C(=O)N(CC)CC)n1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.34
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 2/20 0.32
HSD17B10 Q99714 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TP53 P04637 2/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9378261 0.93 DPP4 (0.36) DPP4KMT2AALDH1A1MEN1PTGDR2
SCHEMBL27485129 0.87 DPP4 (0.33) DPP4SMN1; SMN2LMNAPOLBNPSR1
SCHEMBL2010916 0.86 PTGDR2 (0.34) KMT2AALDH1A1MEN1PTGDR2HTT
SCHEMBL8035572 0.83 HCRTR2 (0.34) DPP4KMT2AALDH1A1PTGDR2KDM4E
SCHEMBL8782525 0.81 KMT2A (0.33) KMT2AALDH1A1MEN1PTGDR2KDM4E
SCHEMBL8782957 0.81 ALDH1A1 (0.33) KMT2AALDH1A1MEN1PTGDR2KDM4E
SCHEMBL8782480 0.81 KMT2A (0.36) KMT2AALDH1A1MEN1PTGDR2KDM4E
Cafenstrole SCHEMBL54625 0.81 KMT2A (0.49) DPP4KMT2AALDH1A1MEN1KDM4E
SCHEMBL8782216 0.79 PTGDR2 (0.32) KMT2AALDH1A1MEN1PTGDR2KDM4E
SCHEMBL8782967 0.79 PTGDR2 (0.34) KMT2AALDH1A1MEN1PTGDR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 585 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5147445-A HERBICIDAL TRIAZOLE COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1992-09-15 US claimed
JP-3090069-A None JP disclosed
EP-2170041-B2 ACTIVE INGREDIENT SUSPENSIONS IN GLYCERINE BAYER CROPSCIENCE AG (DE) 2020-12-23 EP disclosed
EP-3428148-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2020-07-08 EP disclosed
EP-3428148-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2019-01-16 EP disclosed
EP-3088384-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF MERIAL INC (US) 2018-12-12 EP disclosed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 US disclosed
EP-2373157-B1 DISPERSIONS CONTAINING HYDROXYPHENYLPYRUVATE-DIOXYGENASE INHIBITORS BAYER IP GMBH (DE) 2017-08-16 EP disclosed
EP-2167473-B1 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BAYER IP GMBH (DE) 2017-07-05 EP disclosed
EP-3088384-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2016-11-02 EP disclosed
WO-1994006778-A1 HYDROXYL AMINO PHENYL SULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1994-03-31 WO disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 EP disclosed
EP-0562510-A1 Optically active pyrimidinyl- or triazinyl-oxy-(or -thio)-carbonic acid derivatives, processes for their production and their use as herbicides or plant growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-29 EP disclosed
EP-0555770-A1 N-Heteroaryl-N'-(pyrid-2-yl-sulfonyl)-ureas, process for their preparation, and their use as herbicides and plant growth regulators Hoechst Schering AgrEvo GmbH (DE) 1993-08-18 EP disclosed
WO-1993012094-A1 PYRIMIDINYL- OR TRIAZINYL-OXY(OR THIO)ALDEHYDE DERIVATIVES AND THEIR USE AS HERBICIDES OR PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1993-06-24 WO disclosed
EP-0541041-A1 Pyrimidinyl- or triazinyloxy-(or -thio)-carboxylic acids derivatives, process for their preparation and use as herbicides or plant growth regulation agents Hoechst Schering AgrEvo GmbH (DE) 1993-05-12 EP disclosed
US-5147445-A HERBICIDAL TRIAZOLE COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1992-09-15 US disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed
JP-H0390069-A TRIAZOLE COMPOUND AND HERBICIDE CONTAINING THE COMPOUND AS ACTIVE COMPONENT CHUGAI PHARMACEUT CO LTD 1991-04-16 JP disclosed
EP-0332133-A1 Novel triazole compounds, process for producing the same, and herbicidal compositions containing the same Chugai Seiyaku Kabushiki Kaisha (JP) 1989-09-13 EP disclosed