SCHEMBL27485129

SCHEMBL27485129

CCc1cccc(CN)c1S(=O)(=O)c1ncn(C(=O)N(CC)CC)n1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.33
LMNA P02545 1/20 0.32
LOXL2 Q9Y4K0 2/20 0.31
POLB P06746 1/20 0.31
PTBP1 P26599 1/20 0.30
P2RX1 P51575 1/20 0.30
P2RX3 P56373 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
P2RX4 Q99571 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204666 0.87 DPP4 (0.34) DPP4LMNAPOLBSMN1; SMN2NPSR1
SCHEMBL9378261 0.82 DPP4 (0.36) DPP4LMNAPOLBPTBP1P2RX1
SCHEMBL2010916 0.75 PTGDR2 (0.34) POLB
SCHEMBL8035572 0.75 HCRTR2 (0.34) DPP4LMNAPOLBPTBP1P2RX1
SCHEMBL8782671 0.75 POLB (0.34) LMNAPOLBPTBP1P2RX1P2RX3
Cafenstrole SCHEMBL54625 0.75 KMT2A (0.49) DPP4LMNASMN1; SMN2
SCHEMBL9542985 0.74 DPP4 (0.42) DPP4LMNAPOLBPTBP1P2RX1
SCHEMBL7195571 0.74 TDP1 (0.36) DPP4LMNANPSR1
SCHEMBL9015564 0.74 DPP4 (0.34) DPP4
SCHEMBL5376574 0.72 LMNA (0.40) LMNAPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105357968-A Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG 2016-02-24 CN disclosed
CN-101262769-B Storage-stable sulfonamide formulations BAYER CROPSCIENCE AG 2014-06-18 CN disclosed
CN-101583276-B Substituted 1- (3-pyridyl) -pyrazol-4-yl acetic acids, method for the production thereof, and use thereof as herbicides and plant growth regulators BAYER CROPSCIENCE AG 2013-08-28 CN disclosed
CN-101785470-A The composition of phenyl-sulfonylurea herbicide and safener HOECHST SCHERING AGREVO GMBH 2010-07-28 CN disclosed
CN-1269800-C Benzoylcyclohexanediones, process for their preparation and their use as herbicides and plant growth regulators AVENTIS CROPSCIENCE GMBH (DE) 2006-08-16 CN disclosed
CN-1200609-C Substituted aminomethyl phenyl sulphonyl ureas, their production and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 2005-05-11 CN disclosed
CN-1195414-C Combinations of herbicides and safeners AVENTIS CROPSCIENCE GMBH (DE) 2005-04-06 CN disclosed
CN-1326317-A Combinations of herbicides and safeners AVENTIS CROPSCIENCE GMBH (DE) 2001-12-12 CN disclosed
CN-1323292-A Benzoylcyclohexanediones, process for their preparation and their use as herbicides and plant growth regulators AVENTIS CROPSCIENCE GMBH (DE) 2001-11-21 CN disclosed
CN-1317244-A Compsns. for phenyl-sulfonylurea herbicide and safety agent HOECHST SCHERING AGREVO GMBH (DE) 2001-10-17 CN disclosed
CN-1216444-A Substituted aminomethyl phenyl sulphonyl ureas, their production and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1999-05-12 CN disclosed
CN-1162905-A Combinations of phenylsulfonylurea herbicides and safeners HOECHST SCHERING AGREVO GMBH (DE) 1997-10-22 CN disclosed