SCHEMBL2046751

SCHEMBL2046751

CC(=O)ON=C(C)CC(Cc1ccccc1)=NOC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.48
MAPT P10636 2/20 0.48
L3MBTL1 Q9Y468 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
PKM P14618 1/20 0.44
KDM4E B2RXH2 3/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 4/20 0.42
MAPK1 P28482 1/20 0.42
THRB P10828 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2046748 1.00 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1SMN1; SMN2PKM
SCHEMBL18840204 0.89 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1SMN1; SMN2PKM
SCHEMBL9899490 0.86 MEN1 (0.44) ALDH1A1L3MBTL1SMN1; SMN2PKMKDM4E
SCHEMBL9899492 0.86 MEN1 (0.44) ALDH1A1L3MBTL1SMN1; SMN2PKMKDM4E
SCHEMBL18840215 0.85 KDM4E (0.49) ALDH1A1L3MBTL1SMN1; SMN2PKMKDM4E
SCHEMBL19733326 0.85 KDM4E (0.49) ALDH1A1L3MBTL1SMN1; SMN2PKMKDM4E
SCHEMBL14743769 0.85 KDM4E (0.49) ALDH1A1L3MBTL1SMN1; SMN2PKMKDM4E
SCHEMBL13505294 0.79 ALDH1A1 (0.40) ALDH1A1MAPTL3MBTL1SMN1; SMN2PKM
SCHEMBL2043782 0.79 MAPT (0.43) ALDH1A1MAPTL3MBTL1SMN1; SMN2KDM4E
SCHEMBL2043783 0.79 MAPT (0.43) ALDH1A1MAPTL3MBTL1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed