Glycerin

Glycerin

SCHEMBL2046780

C1COCO1.OCC(O)CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
ALDH1A1 P00352 1/20 0.53
THRB P10828 1/20 0.36
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL29085274 0.91 LMNA (0.64) LMNAALDH1A1THRBMAPTATM
Glycerin SCHEMBL830352 0.91
Glycerin SCHEMBL1171535 0.91 LMNA (0.64) LMNAALDH1A1THRBMAPTATM
Glycerin SCHEMBL3943790 0.91 LMNA (0.64) LMNAALDH1A1THRBMAPTATM
Glycerin SCHEMBL29085267 0.91 LMNA (0.64) LMNAALDH1A1THRBMAPTATM
Glycerin SCHEMBL14831862 0.88 LMNA (0.41) LMNAALDH1A1
Glycerin SCHEMBL10396906 0.88 LMNA (0.60) LMNAALDH1A1THRBMAPTATM
Dioxane SCHEMBL1291894 0.88 LMNA (0.60) LMNAALDH1A1THRBMAPTATM
Dioxane SCHEMBL28308269 0.88 LMNA (0.60) LMNAALDH1A1THRBMAPTATM
Glycerin SCHEMBL28000527 0.82 LMNA (0.53) LMNAALDH1A1THRBMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110154725-A1 AGENT FOR INCREASING THE OCTANE NUMBER OF A GASOLINE AUTOMOBILE FUEL EMANUEL INSTITUTE OF BIOCHEMICAL PHYSICS OF RUSSIAN ACADEMY OF SCIENCES (IBCP RAS) (RU) 2011-06-30 US disclosed
US-4281010-A FOR INCREASING BLOOD CIRCULATION DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-07-28 US disclosed